Q&A Is there an interaction between bisphosphonates and proton pump inhibitors?
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From UKMi Medicines Q&A
This updated Medicines Q&A concludes that whilst there is not a recognised interaction between bisphosphonates (B) and PPIs, a common side effect of bisphosphonates is gastro-intestinal disturbance. Additionally the SPCs for B and PPIs highlight an increased risk of fractures.
Is there an interaction between bisphosphonates and proton pump inhibitors?