Orphenadrine 50mg tablets unavailable

10 June 2016

Disipal® (Orphenadrine) 50mg tablets have been discontinued and are no longer available. There is a generic version of Orphenadrine 50mg tablets but they are also currently unavailable due to a manufacturing problem (Not expected to be in stock before October 2016).

We would advise all prescribers to review any patient currently prescribed orphenadrine.

NTW have advised that consideration can be given to changing to a suitable alternative such as procyclidine or trihexiphenidyl.  If a switch to a therapeutic alternative is not clinically appropriate limited supplies of orphenadrine liquid (5mg/5ml – 150ml bottle) may be available.