Welcome to the Medicines Optimisation website

This website is maintained by North of England Commissioning Support Medicines Optimisation Team and contains medicines information guidelines and resources to support safe, effective and good value medicines use in primary care in North East and Cumbria CCGs.

MHRA Drug Safety Update January 2017

The January 2017 MHRA Drug Safety Update contains advice for healthcare professionals on:

– Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
– Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
– Apremilast (Otezla ▼): risk of suicidal thoughts and behaviour
– Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC

Sepsis toolkit for GPs – a reminder

The Royal College of General Practitioners (RCGP), in partnership with Health Education England and NHS England, recently launched a new sepsis toolkit to support GPs and healthcare professionals to identify and manage the condition in patients.