Welcome to the Medicines Optimisation website

This website is maintained by North of England Commissioning Support Medicines Optimisation Team and contains medicines information guidelines and resources to support safe, effective and good value medicines use in primary care in North East and Cumbria CCGs.


MHRA Drug Safety Update June 2017

A new Medicines and Healthcare products Regulatory Agency (MHRA) Drug Safety Update (vol 10, issue 11, June 2017) has been published and includes articles on:

  • Denosumab (Prolia, Xgeva▼): reports of osteonecrosis of the external auditory canal
  • Brimonidine gel (Mirvaso): risk of systemic cardiovascular effects; not to be applied to damaged skin
  • Pseudoephedrine and ephedrine: regular review of minimising risk of misuse in the UK
  • e-cigarettes and refill containers (e-liquids): report suspected side effects and safety concerns
  • Letters sent to healthcare professionals in May 2017
  • Medical Device Alerts issued in May 2017

MicroGuide Antibiotics Guideline App Feedback

We are evaluating the MicroGuide Antibiotics App and need your feedback on how useful you find the app and anything you would like to see changed.  The survey takes a maximum of 5 minutes to complete and can be found on the link below: https://www.surveymonkey.co.uk/r/NECSMGuide 


CAS Alert: Influenza Season 2016/17: Use of Antiviral Medicines

The most recent surveillance data from Public Health England (PHE) indicates that circulation of influenza in the community has returned to baseline levels.

The Department of Health has issued a CAS alert stating GPs and other prescribers working in primary care should no longer prescribe antiviral medicines for the prophylaxis and treatment of influenza on an FP10 prescription form. Community pharmacists should no longer supply antiviral medicines in primary care on presentation of an FP10 prescription form.

This advice stands until the Department of Health write again to re-commence prescribing and supply of antiviral medicines in primary care.

RightBreathe website

The RightBreathe website and app has been developed by Lambeth GP, Dr Azhar Saleem, in conjunction with (amongst others) UK Medicines Information. Both the website and app have now been launched, and with details on every licensed inhaler in the UK for asthma and COPD, including links to videos and prescribing information, they provide a free-to-use, comprehensive, ‘one-stop’ Continue Reading »