Unlicensed Liquid Medicines for Children – use of non-standard strengths

Analysis of prescribing of unlicensed liquid medicines for children across NECS-linked CCGs in the North of England has revealed considerable use of ‘non-standard‘ strengths – i.e. strengths other than those recommended by the Royal College of Paediatrics & Child Health (RCPCH) and the Neonatal & Paediatric Pharmacists Group (NPPG).

The table below lists the ten unlicensed liquid medicines most frequently prescribed for children across NECS-linked CCGs, with the proportion prescribed at one of the RCPCH/NPPG standard strengths listed in the BNFC.

Liquid Medicine Prescriptions for children @ Standard Strength
Melatonin 88%
Omeprazole 21%
Spironolactone 50%
Chloral Hydrate 1%
Hydrocortisone 93%
Midazolam Maleate 0%
Phenobarbital 65%
Azathioprine 98%
Clopidogrel 6%
Tacrolimus 100%