Tag Archives: shortage

Supply Disruption Alert – EpiPen adrenaline auto-injectors

The Department of Health & Social Care (DHSC) have issued the attached Supply Disruption Alert (SDA) with advice on managing issues due to shortage of EpiPen adrenaline auto-injectors.

DownloadThe SDA recommends that all health care professionals ensure that:

  1. Adult and child adrenaline auto-injectors are only prescribed and dispensed to those who truly need them.
  2. Repeat prescriptions and supply are managed diligently and patients advised that:
    • they should NOT dispose of their expired devices until they have replaced them.
    • adrenaline auto-injectors expire on the last day of the month indicated – a device labelled ‘April 2019’ does not expire until the end of April 2019.
    • The MHRA have extended the use by date of certain batches of adult EpiPen by four months (see below or here).
LOT Labelled Expiry Date (end of the month) Extended Use by Date (end of the month)
6FA794J 07.2018 11.2018
6FA795Y 07.2018 11.2018
7FA112F 09.2018 01.2019
7FA106B 09.2018 01.2019
7FA283B 10.2018 02.2019
7FA251D 10.2018 02.2019
7FA250B 10.2018 02.2019
7FA265C 11.2018 03.2019
7FA265B 11.2018 03.2019
  1. Where possible, prescribers should not prescribe a replacement adult EpiPen whilst the original is within the extended use by date.
  2. Some adults and children may need to switch from their usual device to alternative adrenaline auto-injector devices. The different brands of adrenaline auto-injectors are not used in exactly the same way and specific training and advice is required. See attached guidance.
  3. Junior adrenaline auto-injectors (150mcg) must only be dispensed to children under 30kg, in line with the existing established guidance. Other children weighing more than 30kg need to be given adult auto-injectors (300mcg). See attached guidance & BSACI guideline.
  4. Prescribers should work in close collaboration with local pharmacies to understand which devices are available. Prescribers and pharmacists should work together to ensure patients who are switched to an alternative device are trained appropriately and understand how to use the new device.
  5. Prescribers and pharmacies should regularly check the Specialist Pharmacy Services website for updates: https://www.sps.nhs.uk/articles/shortage-of-epipen/

Cyclizine Lactate 50 mg/ml Injection Shortage – Information for Prescribers

There is a delay to the delivery of cyclizine injection 50mg/ml and stock is now expected in Jan 2016. The company anticipates being out of stock for between 2 to 4 weeks.

Click here for more information from UKMi which provides prescribers with more information and suggests:

“In order to preserve existing stock for critical areas, cyclizine may need to be restricted for palliative care use and no longer used as a first line antiemetic in areas where alternatives antiemetics are available, such as using ondansetron for post operative N&V. Advice should be sought from the relevant specialist team in the event of a shortage. Importers are currently investigating availability of cyclizine from outside the UK.”