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New and updated medicines optimisation ‘Key Therapeutic Topics’

Medicines optimisation: key therapeutic topics summarise the evidence-base on topics identified to support medicines optimisation, but are not formal NICE guidance.

These topics are selected and prioritised therapeutic areas where there are potential opportunities for maintaining or improving quality and improving value from our use of medicines. Releasing resources from one area of health care whilst maintaining or improving quality of care means those resources are available for use elsewhere, for example – the prescribing of innovative medicines.

The following new Key Therapeutic Topics have been published:

  • Multimorbidity and polypharmacy
  • Psychotropic medicines in people with learning disabilities
  • Safer insulin prescribing
  • Medicines optimisation in long-term pain

The following Key Therapeutic Topics have been updated:

  • Type 2 diabetes mellitus: medicines optimisation priorities
  • Non-steroidal anti-inflammatory drugs
  • Wound care products
  • Biosimilar medicines
  • Anticoagulants, including non-vitamin K antagonist oral anticoagulants (NOACs)
  • Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI
  • Lipid-modifying drugs
  • Asthma: medicines optimisation priorities
  • Hypnotics
  • Low-dose antipsychotics in people with dementia
  • Antimicrobial stewardship: prescribing antibiotics

NICE: Key Therapeutic Topics